Loss of Hsp70 Exacerbates Pathogenesis But Not Levels of Fibrillar Aggregates in a Mouse Model of Huntington's Disease

Endogenous protein quality control machinery has long been suspected of influencing the onset and progression of neurodegenerative diseases characterized by accumulation of misfolded proteins. Huntington's disease (HD) is a fatal neurodegenerative disorder caused by an expansion of a polyglutam...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wacker, Jennifer L., Huang, Shao-Yi, Steele, Andrew D., Aron, Rebecca, Lotz, Gregor P., Nguyen, QuangVu, Giorgini, Flaviano, Roberson, Erik D., Lindquist, Susan, Masliah, Eliezer, Muchowski, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739279/
https://ncbi.nlm.nih.gov/pubmed/19605647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2250-09.2009
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados