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Programming tumor-reactive effector memory CD8(+) T cells in vitro obviates the requirement for in vivo vaccination
Naive and memory CD8(+) T cells can undergo programmed activation and expansion in response to a short T-cell receptor stimulus, but the extent to which in vitro programming can qualitatively substitute for an in vivo antigen stimulation remains unknown. We show that self-/tumor-reactive effector me...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2738567/ https://ncbi.nlm.nih.gov/pubmed/19561320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-192419 |
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