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No Sib Pair Concordance for Breast or Ovarian Cancer in BRCA1 Mutation Carriers
Modifying factors might theoretically determine whether a BRCA1 mutation carrier contracts breast or ovarian cancer. If so, one would expect concordance for breast or ovarian cancer in affected sibships. We identified 64 pairs with cancers where one or both sisters were demonstrated to carry a BRCA1...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736994/ https://ncbi.nlm.nih.gov/pubmed/19725986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-5-2-67 |
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