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No Sib Pair Concordance for Breast or Ovarian Cancer in BRCA1 Mutation Carriers

Modifying factors might theoretically determine whether a BRCA1 mutation carrier contracts breast or ovarian cancer. If so, one would expect concordance for breast or ovarian cancer in affected sibships. We identified 64 pairs with cancers where one or both sisters were demonstrated to carry a BRCA1...

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Hlavní autoři: Møller, Pål, Mæhle, Lovise, Clark, Neal, Apold, Jaran
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736994/
https://ncbi.nlm.nih.gov/pubmed/19725986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-5-2-67
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