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Germline PTEN mutations are rare and highly penetrant

Cowden syndrome (multiple hamartoma syndrome, MIM 158350) is an early onset syndrome characterized by multiple hamartomas in the skin, mucous membranes, breast, thyroid and endometrium. Patients with Cowden syndrome have increased risk of breast cancer, thyroid cancer and endometrial cancer. In 1997...

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Detalhes bibliográficos
Main Authors: Rustad, Cecilie F, Bjørnslett, Merete, Heimdal, Ketil R, Mæhle, Lovise, Apold, Jaran, Møller, Pål
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837306/
https://ncbi.nlm.nih.gov/pubmed/20223021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-4-4-177
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