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Germline PTEN mutations are rare and highly penetrant

Cowden syndrome (multiple hamartoma syndrome, MIM 158350) is an early onset syndrome characterized by multiple hamartomas in the skin, mucous membranes, breast, thyroid and endometrium. Patients with Cowden syndrome have increased risk of breast cancer, thyroid cancer and endometrial cancer. In 1997...

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Bibliografske podrobnosti
Main Authors: Rustad, Cecilie F, Bjørnslett, Merete, Heimdal, Ketil R, Mæhle, Lovise, Apold, Jaran, Møller, Pål
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837306/
https://ncbi.nlm.nih.gov/pubmed/20223021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-4-4-177
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