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No Sib Pair Concordance for Breast or Ovarian Cancer in BRCA1 Mutation Carriers

Modifying factors might theoretically determine whether a BRCA1 mutation carrier contracts breast or ovarian cancer. If so, one would expect concordance for breast or ovarian cancer in affected sibships. We identified 64 pairs with cancers where one or both sisters were demonstrated to carry a BRCA1...

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Detalhes bibliográficos
Principais autores: Møller, Pål, Mæhle, Lovise, Clark, Neal, Apold, Jaran
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736994/
https://ncbi.nlm.nih.gov/pubmed/19725986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-5-2-67
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