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No Sib Pair Concordance for Breast or Ovarian Cancer in BRCA1 Mutation Carriers

Modifying factors might theoretically determine whether a BRCA1 mutation carrier contracts breast or ovarian cancer. If so, one would expect concordance for breast or ovarian cancer in affected sibships. We identified 64 pairs with cancers where one or both sisters were demonstrated to carry a BRCA1...

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Autors principals: Møller, Pål, Mæhle, Lovise, Clark, Neal, Apold, Jaran
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736994/
https://ncbi.nlm.nih.gov/pubmed/19725986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1897-4287-5-2-67
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