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The Class II Phosphatidylinositol 3 kinase C2β Is Required for the Activation of the K(+) Channel KCa3.1 and CD4 T-Cells
The Ca(2+)-activated K(+) channel KCa3.1 is required for Ca(2+) influx and the subsequent activation of T-cells. We previously showed that nucleoside diphosphate kinase beta (NDPK-B), a mammalian histidine kinase, directly phosphorylates and activates KCa3.1 and is required for the activation of hum...
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| Autori principali: | , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Cell Biology
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2735477/ https://ncbi.nlm.nih.gov/pubmed/19587117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-05-0390 |
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