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Inhibition of the K(+) channel KCa3.1 ameliorates T cell–mediated colitis
The calcium-activated K(+) channel KCa3.1 plays an important role in T lymphocyte Ca(2+) signaling by helping to maintain a negative membrane potential, which provides an electrochemical gradient to drive Ca(2+) influx. To assess the role of KCa3.1 channels in lymphocyte activation in vivo, we studi...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824388/ https://ncbi.nlm.nih.gov/pubmed/20080610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910133107 |
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