Nucleoside Diphosphate Kinase B Knock-out Mice Have Impaired Activation of the K(+) Channel KCa3.1, Resulting in Defective T Cell Activation

Nucleoside diphosphate kinases (NDPKs) are encoded by the Nme (non-metastatic cell) gene family. Although they comprise a family of 10 genes, NDPK-A and -B are ubiquitously expressed and account for most of the NDPK activity. We previously showed that NDPK-B activates the K(+) channel KCa3.1 via his...

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Detalhes bibliográficos
Main Authors: Di, Lie, Srivastava, Shekhar, Zhdanova, Olga, Sun, Yi, Li, Zhai, Skolnik, Edward Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998118/
https://ncbi.nlm.nih.gov/pubmed/20884616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.168070
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