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Protein histidine phosphatase 1 negatively regulates CD4 T cells by inhibiting the K(+) channel KCa3.1
The calcium activated K(+) channel KCa3.1 plays an important role in T lymphocyte Ca(2+) signaling by helping to maintain a negative membrane potential, which provides an electrochemical gradient to drive Ca(2+) influx. We previously showed that nucleoside diphosphate kinase beta (NDPK-B), a mammali...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2538450/ https://ncbi.nlm.nih.gov/pubmed/18796614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803678105 |
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