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The Lymphocyte Potassium Channels Kv1.3 and KCa3.1 as Targets for Immunosuppression

The voltage-gated Kv1.3 and the calcium-activated KCa3.1 potassium channel modulate many calcium-dependent cellular processes in immune cells, including T-cell activation and proliferation, and have therefore been proposed as novel therapeutic targets for immunomodulation. Kv1.3 is highly expressed...

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Detalhes bibliográficos
Main Authors: Lam, Jenny, Wulff, Heike
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3253536/
https://ncbi.nlm.nih.gov/pubmed/22241939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ddr.20467
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