The Class II Phosphatidylinositol 3 kinase C2β Is Required for the Activation of the K(+) Channel KCa3.1 and CD4 T-Cells

The Ca(2+)-activated K(+) channel KCa3.1 is required for Ca(2+) influx and the subsequent activation of T-cells. We previously showed that nucleoside diphosphate kinase beta (NDPK-B), a mammalian histidine kinase, directly phosphorylates and activates KCa3.1 and is required for the activation of hum...

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Détails bibliographiques
Auteurs principaux: Srivastava, Shekhar, Di, Lie, Zhdanova, Olga, Li, Zhai, Vardhana, Santosha, Wan, Qi, Yan, Ying, Varma, Rajat, Backer, Jonathan, Wulff, Heike, Dustin, Michael L., Skolnik, Edward Y.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2009
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2735477/
https://ncbi.nlm.nih.gov/pubmed/19587117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-05-0390
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