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Molecular determinants of fast Ca(2+)-dependent inactivation and gating of the Orai channels
Ca(2+) influx by store-operated Ca(2+) influx channels (SOCs) mediates many cellular functions regulated by Ca(2+), and excessive SOC-mediated Ca(2+) influx is cytotoxic and associated with disease. One form of SOC is the CRAC current that is mediated by Orai channels activated by STIM1. A fundament...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2732841/ https://ncbi.nlm.nih.gov/pubmed/19706554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904664106 |
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