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SOAR and the polybasic STIM1 domains gate and regulate the Orai channels

Store-operated Ca(2+) influx is mediated by store002Doperated Ca(2+) channels (SOCs) and is a central component of receptor-evoked Ca(2+) signals1. The Orai channels mediate SOCs2–4 and STIM1 is the ER-resident Ca(2+) sensor that gates the channels5, 6. How STIM1 gates and regulates the Orai channel...

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Detalhes bibliográficos
Main Authors: Yuan, Joseph P., Zeng, Weizhong, Dorwart, Michael R., Choi, Young-Jin, Worley, Paul F., Muallem, Shmuel
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663385/
https://ncbi.nlm.nih.gov/pubmed/19182790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1842
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