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SOAR and the polybasic STIM1 domains gate and regulate the Orai channels
Store-operated Ca(2+) influx is mediated by store002Doperated Ca(2+) channels (SOCs) and is a central component of receptor-evoked Ca(2+) signals1. The Orai channels mediate SOCs2–4 and STIM1 is the ER-resident Ca(2+) sensor that gates the channels5, 6. How STIM1 gates and regulates the Orai channel...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2663385/ https://ncbi.nlm.nih.gov/pubmed/19182790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1842 |
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