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The STIM1 CTID domain determines access of SARAF to SOAR to regulate Orai1 channel function
Ca(2+) influx by store-operated Ca(2+) channels (SOCs) mediates all Ca(2+)-dependent cell functions, but excess Ca(2+) influx is highly toxic. The molecular components of SOC are the pore-forming Orai1 channel and the endoplasmic reticulum Ca(2+) sensor STIM1. Slow Ca(2+)-dependent inactivation (SCD...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3704993/ https://ncbi.nlm.nih.gov/pubmed/23816623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201301148 |
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