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Native Store-operated Ca(2+) Influx Requires the Channel Function of Orai1 and TRPC1
With the discovery of STIM1 and Orai1 and gating of both TRPC and Orai1 channels by STIM1, a central question is the role of each of the channels in the native store-operated Ca(2+) influx (SOCs). Here, we used a strategy of knockdown of Orai1 and of TRPC1 alone and in combination and rescue by smal...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665094/ https://ncbi.nlm.nih.gov/pubmed/19228695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808097200 |
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