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Intrinsic tumor suppression and epithelial maintenance by endocytic activation of Eiger/TNF signaling in Drosophila
Oncogenic alterations that confer proliferative advantages in epithelial tissues also often trigger apoptosis, suggesting an evolutionary mechanism by which organisms eliminate aberrant cells from epithelia. However, the underlying mechanism of how these tissues eliminate oncogenic cells remains to...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2729686/ https://ncbi.nlm.nih.gov/pubmed/19289090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.01.002 |
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