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Bax-like protein Drob-1 protects neurons from expanded polyglutamine-induced toxicity in Drosophila
Bcl-2 family proteins regulate cell death through the mitochondrial apoptotic pathway. Here, we show that the Drosophila Bax-like Bcl-2 family protein Drob-1 maintains mitochondrial function to protect cells from neurodegeneration. A pan-neuronal knockdown of Drob-1 results in lower locomotor activi...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2005
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1176450/ https://ncbi.nlm.nih.gov/pubmed/16001086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600721 |
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