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Polyglutamine toxicity in non-neuronal cells

The neurodegenerative polyglutamine diseases are caused by an expansion of unstable polyglutamine repeats in various disease proteins. Although these mutant proteins are expressed ubiquitously in neuronal and non-neuronal cells, they cause selective degeneration of specific neuronal populations. Rec...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bradford, Jennifer W, Li, Shihua, Li, Xiao-Jiang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074229/
https://ncbi.nlm.nih.gov/pubmed/20231860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2010.32
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