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Nuclear accumulation of polyglutamine disease proteins and neuropathology

There are nine inherited neurodegenerative disorders caused by polyglutamine (polyQ) expansion in various disease proteins. Although these polyglutamine proteins have different functions and are localized in different subcellular regions, all the polyQ diseases share a common pathological feature: t...

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Detalhes bibliográficos
Main Authors: Havel, Lauren S, Li, Shihua, Li, Xiao-Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714308/
https://ncbi.nlm.nih.gov/pubmed/19575804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-2-21
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