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Polyglutamine toxicity in non-neuronal cells
The neurodegenerative polyglutamine diseases are caused by an expansion of unstable polyglutamine repeats in various disease proteins. Although these mutant proteins are expressed ubiquitously in neuronal and non-neuronal cells, they cause selective degeneration of specific neuronal populations. Rec...
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Main Authors: | , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2010
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3074229/ https://ncbi.nlm.nih.gov/pubmed/20231860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2010.32 |
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