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Astrocyte expression of the Drosophila TNF-alpha homologue, Eiger, regulates sleep in flies

Sleep contributes to cognitive functioning and is sufficient to alter brain morphology and function. However, mechanisms underlying sleep regulation remain poorly understood. In mammals, tumor necrosis factor-alpha (TNFα) is known to regulate sleep, and cytokine expression may represent an evolution...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Vanderheyden, William M., Goodman, Alan G., Taylor, Rebecca H., Frank, Marcos G., Van Dongen, Hans P. A., Gerstner, Jason R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6209136/
https://ncbi.nlm.nih.gov/pubmed/30379810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007724
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