Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway

Drosophila provides a powerful genetic model for studying the in vivo regulation of cell death. In our large-scale gain-of-function screen, we identified Eiger, the first invertebrate tumor necrosis factor (TNF) superfamily ligand that can induce cell death. Eiger is a type II transmembrane protein...

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Bibliographic Details
Main Authors: Igaki, Tatsushi, Kanda, Hiroshi, Yamamoto-Goto, Yuki, Kanuka, Hirotaka, Kuranaga, Erina, Aigaki, Toshiro, Miura, Masayuki
Format: Artigo
Language:Inglês
Published: Oxford University Press 2002
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC126061/
https://ncbi.nlm.nih.gov/pubmed/12065414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf306
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