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Intrinsic tumor suppression and epithelial maintenance by endocytic activation of Eiger/TNF signaling in Drosophila

Oncogenic alterations that confer proliferative advantages in epithelial tissues also often trigger apoptosis, suggesting an evolutionary mechanism by which organisms eliminate aberrant cells from epithelia. However, the underlying mechanism of how these tissues eliminate oncogenic cells remains to...

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Detalhes bibliográficos
Main Authors: Igaki, Tatsushi, Pastor-Pareja, Jose Carlos, Aonuma, Hiroka, Miura, Masayuki, Xu, Tian
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729686/
https://ncbi.nlm.nih.gov/pubmed/19289090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.01.002
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