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Intrinsic tumor suppression and epithelial maintenance by endocytic activation of Eiger/TNF signaling in Drosophila

Oncogenic alterations that confer proliferative advantages in epithelial tissues also often trigger apoptosis, suggesting an evolutionary mechanism by which organisms eliminate aberrant cells from epithelia. However, the underlying mechanism of how these tissues eliminate oncogenic cells remains to...

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Dettagli Bibliografici
Autori principali: Igaki, Tatsushi, Pastor-Pareja, Jose Carlos, Aonuma, Hiroka, Miura, Masayuki, Xu, Tian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729686/
https://ncbi.nlm.nih.gov/pubmed/19289090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.01.002
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