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Functional Dynamics of the Folded Ankyrin Repeats of IκBα Revealed by Nuclear Magnetic Resonance
[Image: see text] Inhibition of nuclear factor κB (NF-κB) is mainly accomplished by IκBα, which consists of a signal response sequence at the N-terminus, a six-ankyrin repeat domain (ARD) that binds NF-κB, and a C-terminal PEST sequence. Previous studies with the ARD revealed that the fifth and sixt...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical Society
2009
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728578/ https://ncbi.nlm.nih.gov/pubmed/19591507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900712r |
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