Anchoring Fusion Thrombomodulin to the Endothelial Lumen Protects against Injury-induced Lung Thrombosis and Inflammation

Rationale: Endothelial thrombomodulin (TM) regulates thrombosis and inflammation. Diverse forms of pulmonary and vascular injury are accompanied by down-regulation of TM, which aggravates tissue injury. We postulated that anchoring TM to the endothelial surface would restore its protective functions...

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Detalhes bibliográficos
Main Authors: Ding, Bi-Sen, Hong, Nankang, Christofidou-Solomidou, Melpo, Gottstein, Claudia, Albelda, Steven M., Cines, Douglas B., Fisher, Aron B., Muzykantov, Vladimir R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2009
Assuntos:
C. Critical Care
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724717/
https://ncbi.nlm.nih.gov/pubmed/19342415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200809-1433OC
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