Modulation of endothelial targeting by size of antibody-antioxidant enzyme conjugates

Endothelial targeting of antioxidant enzymes attenuates acute vascular oxidative stress in animal studies. Superoxide dismutase (SOD) and catalase conjugated with antibodies to Platelet-Endothelial Cell Adhesion Molecule-1 (anti-PECAM/SOD and anti-PECAM/catalase) bind to endothelium, accumulate in t...

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Bibliographic Details
Main Authors: Shuvaev, Vladimir V., Tliba, Samira, Pick, Jeremy, Arguiri, Evguenia, Christofidou-Solomidou, Melpo, Albelda, Steven M., Muzykantov, Vladimir R.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043111/
https://ncbi.nlm.nih.gov/pubmed/21044652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2010.10.026
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