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HLA-Associated Immune Escape Pathways in HIV-1 Subtype B Gag, Pol and Nef Proteins

BACKGROUND: Despite the extensive genetic diversity of HIV-1, viral evolution in response to immune selective pressures follows broadly predictable mutational patterns. Sites and pathways of Human Leukocyte-Antigen (HLA)-associated polymorphisms in HIV-1 have been identified through the analysis of...

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Hlavní autoři: Brumme, Zabrina L., John, Mina, Carlson, Jonathan M., Brumme, Chanson J., Chan, Dennison, Brockman, Mark A., Swenson, Luke C., Tao, Iris, Szeto, Sharon, Rosato, Pamela, Sela, Jennifer, Kadie, Carl M., Frahm, Nicole, Brander, Christian, Haas, David W., Riddler, Sharon A., Haubrich, Richard, Walker, Bruce D., Harrigan, P. Richard, Heckerman, David, Mallal, Simon
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723923/
https://ncbi.nlm.nih.gov/pubmed/19690614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006687
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