HLA-Associated Immune Escape Pathways in HIV-1 Subtype B Gag, Pol and Nef Proteins

BACKGROUND: Despite the extensive genetic diversity of HIV-1, viral evolution in response to immune selective pressures follows broadly predictable mutational patterns. Sites and pathways of Human Leukocyte-Antigen (HLA)-associated polymorphisms in HIV-1 have been identified through the analysis of...

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Main Authors: Brumme, Zabrina L., John, Mina, Carlson, Jonathan M., Brumme, Chanson J., Chan, Dennison, Brockman, Mark A., Swenson, Luke C., Tao, Iris, Szeto, Sharon, Rosato, Pamela, Sela, Jennifer, Kadie, Carl M., Frahm, Nicole, Brander, Christian, Haas, David W., Riddler, Sharon A., Haubrich, Richard, Walker, Bruce D., Harrigan, P. Richard, Heckerman, David, Mallal, Simon
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723923/
https://ncbi.nlm.nih.gov/pubmed/19690614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006687
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