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Host Genetic Determinants of T Cell Responses to the MRKAd5 HIV-1 gag/pol/nef Vaccine in the Step Trial

Understanding how human genetic variation impacts individual response to immunogens is fundamental for rational vaccine development. To explore host mechanisms involved in cellular immune responses to the MRKAd5 human immunodeficiency virus type 1 (HIV-1) gag/pol/nef vaccine tested in the Step trial...

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Autors principals: Fellay, Jacques, Frahm, Nicole, Shianna, Kevin V., Cirulli, Elizabeth T., Casimiro, Danilo R., Robertson, Michael N., Haynes, Barton F., Geraghty, Daniel E., McElrath, M. Juliana, Goldstein, David B.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071133/
https://ncbi.nlm.nih.gov/pubmed/21278214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiq125
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