Efficacy of the HSP90 inhibitor 17-AAG in human glioma cell lines and tumorigenic glioma stem cells

Glioblastoma multiforme (GBM) arises from genetic and signaling abnormalities in components of signal transduction pathways involved in proliferation, survival, and the cell cycle axis. Studies to date with single-agent targeted molecular therapy have revealed only modest effects in attenuating the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sauvageot, Claire Marie-Elisabeth, Weatherbee, Jessica Leigh, Kesari, Santosh, Winters, Susan Elizabeth, Barnes, Jessica, Dellagatta, Jamie, Ramakrishna, Naren Raj, Stiles, Charles Dean, Kung, Andrew Li-Jen, Kieran, Mark W., Wen, Patrick Yung Chih
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Duke University Press 2009
Pynciau:
Basic and Translational Investigations
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718982/
https://ncbi.nlm.nih.gov/pubmed/18682579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-060
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg