Lonafarnib (SCH66336) improves the activity of temozolomide and radiation for orthotopic malignant gliomas

Malignant gliomas are highly lethal tumors resistant to current therapies. The standard treatment modality for these tumors, surgical resection followed by radiation therapy and concurrent temozolomide, has demonstrated activity, but development of resistance and disease progression is common. Altho...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurooncol
Prif Awduron: Chaponis, Deviney, Barnes, Jessica W., Dellagatta, Jamie L., Kesari, Santosh, Fast, Eva, Sauvageot, Claire, Panagrahy, Dipak, Ramakrishna, Naren, Wen, Patrick Y., Kung, Andrew L., Stiles, Charles, Kieran, Mark W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898271/
https://ncbi.nlm.nih.gov/pubmed/21246394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-010-0502-4
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