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Lonafarnib (SCH66336) improves the activity of temozolomide and radiation for orthotopic malignant gliomas

Malignant gliomas are highly lethal tumors resistant to current therapies. The standard treatment modality for these tumors, surgical resection followed by radiation therapy and concurrent temozolomide, has demonstrated activity, but development of resistance and disease progression is common. Altho...

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Detalhes bibliográficos
Publicado no:J Neurooncol
Main Authors: Chaponis, Deviney, Barnes, Jessica W., Dellagatta, Jamie L., Kesari, Santosh, Fast, Eva, Sauvageot, Claire, Panagrahy, Dipak, Ramakrishna, Naren, Wen, Patrick Y., Kung, Andrew L., Stiles, Charles, Kieran, Mark W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4898271/
https://ncbi.nlm.nih.gov/pubmed/21246394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-010-0502-4
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