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Inhibition of cell growth in human glioblastoma cell lines by farnesyltransferase inhibitor SCH66336.

Ras activation occurs through stimulation of an upstream growth factor receptor such as epidermal growth factor receptor (EGFR). The ultimate effect of Ras is to induce nuclear transcription via a signaling pathway sequentially involving Raf, MAP kinase kinase (MEK), and mitogen-activated protein ki...

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書誌詳細
主要な著者: Glass, T. L., Liu, T. J., Yung, W. K.
フォーマット: Artigo
言語:Inglês
出版事項: 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1920495/
https://ncbi.nlm.nih.gov/pubmed/11302335
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