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Farnesyltransferase inhibitor R115777 inhibits cell growth and induces apoptosis in mantle cell lymphoma

The cytotoxic activity of the farnesyltranseferase inhibitor R115777 was evaluated in cell lines representative of mantle cell lymphoma (MCL). Cell growth, proliferation, and apoptosis were analyzed in four human MCL cell lines (Granta, NCEB, REC, and UPN1) in presence of R115777, alone or in combin...

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Autores principales: Rolland, Delphine, Camara-Clayette, Valérie, Barbarat, Aurélie, Salles, Gilles, Coiffier, Bertrand, Ribrag, Vincent, Thieblemont, Catherine
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Verlag 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705670/
https://ncbi.nlm.nih.gov/pubmed/17639395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-007-0543-3
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