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MurF Inhibitors with Antibacterial Activity: Effect on Muropeptide Levels
MurF catalyzes the last cytoplasmic step of bacterial cell wall synthesis and is essential for bacterial survival. Our previous studies used a pharmacophore model of a MurF inhibitor to identify additional inhibitors with improved properties. We now present the characterization of two such inhibitor...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2009
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715636/ https://ncbi.nlm.nih.gov/pubmed/19470511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00166-09 |
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