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A MurF Inhibitor That Disrupts Cell Wall Biosynthesis in Escherichia coli
MurF is an essential enzyme of bacterial cell wall biosynthesis. Few MurF inhibitors have been reported, and none have displayed measurable antibacterial activity. Through the use of a MurF binding assay, a series of 8-hydroxyquinolines that bound to the Escherichia coli enzyme and inhibited its act...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2167990/ https://ncbi.nlm.nih.gov/pubmed/17908943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00845-07 |
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