A MurF Inhibitor That Disrupts Cell Wall Biosynthesis in Escherichia coli

MurF is an essential enzyme of bacterial cell wall biosynthesis. Few MurF inhibitors have been reported, and none have displayed measurable antibacterial activity. Through the use of a MurF binding assay, a series of 8-hydroxyquinolines that bound to the Escherichia coli enzyme and inhibited its act...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Baum, Ellen Z., Crespo-Carbone, Steven M., Klinger, Alexandra, Foleno, Barbara D., Turchi, Ignatius, Macielag, Mark, Bush, Karen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2007
Aiheet:
Mechanisms of Action: Physiological Effects
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2167990/
https://ncbi.nlm.nih.gov/pubmed/17908943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00845-07
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia