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Phage display-derived inhibitor of the essential cell wall biosynthesis enzyme MurF
BACKGROUND: To develop antibacterial agents having novel modes of action against bacterial cell wall biosynthesis, we targeted the essential MurF enzyme of the antibiotic resistant pathogen Pseudomonas aeruginosa. MurF catalyzes the formation of a peptide bond between D-Alanyl-D-Alanine (D-Ala-D-Ala...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2626591/ https://ncbi.nlm.nih.gov/pubmed/19099588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-9-33 |
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