Identification and Characterization of New Inhibitors of the Escherichia coli MurA Enzyme

The bacterial enzyme MurA catalyzes the transfer of enolpyruvate from phosphoenolpyruvate (PEP) to uridine diphospho-N-acetylglucosamine (UNAG), which is the first committed step of bacterial cell wall biosynthesis. From high-throughput screening of a chemical library, three novel inhibitors of the...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Baum, Ellen Z., Montenegro, Deborah A., Licata, Lisa, Turchi, Ignatius, Webb, Glenda C., Foleno, Barbara D., Bush, Karen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Mechanisms of Action: Physiological Effects
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC90801/
https://ncbi.nlm.nih.gov/pubmed/11600375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.11.3182-3188.2001
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky