Identification and Characterization of New Inhibitors of the Escherichia coli MurA Enzyme
The bacterial enzyme MurA catalyzes the transfer of enolpyruvate from phosphoenolpyruvate (PEP) to uridine diphospho-N-acetylglucosamine (UNAG), which is the first committed step of bacterial cell wall biosynthesis. From high-throughput screening of a chemical library, three novel inhibitors of the...
保存先:
| 出版年: | Antimicrob Agents Chemother |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
2001
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90801/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11600375/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.11.3182-3188.2001 |
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