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Identification of a Dithiazoline Inhibitor of Escherichia coli l,d-Carboxypeptidase A
The enzyme l,d-carboxypeptidase A is involved in the recycling of bacterial peptidoglycan and is essential in Escherichia coli during stationary phase. By high-throughput screening, we have identified a dithiazoline inhibitor of the enzyme with a 50% inhibitory concentration of 3 μM. The inhibitor a...
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| Huvudupphovsmän: | , , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Microbiology
2005
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1280138/ https://ncbi.nlm.nih.gov/pubmed/16251288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.11.4500-4507.2005 |
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