Identification of a Dithiazoline Inhibitor of Escherichia coli l,d-Carboxypeptidase A

The enzyme l,d-carboxypeptidase A is involved in the recycling of bacterial peptidoglycan and is essential in Escherichia coli during stationary phase. By high-throughput screening, we have identified a dithiazoline inhibitor of the enzyme with a 50% inhibitory concentration of 3 μM. The inhibitor a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Baum, Ellen Z., Crespo-Carbone, Steven M., Foleno, Barbara, Peng, Sean, Hilliard, Jamese J., Abbanat, Darren, Goldschmidt, Raul, Bush, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280138/
https://ncbi.nlm.nih.gov/pubmed/16251288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.11.4500-4507.2005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados