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Somatic expansion of the Huntington's disease CAG repeat in the brain is associated with an earlier age of disease onset
The age of onset of Huntington's disease (HD) is determined primarily by the length of the HD CAG repeat mutation, but is also influenced by other modifying factors. Delineating these modifiers is a critical step towards developing validated therapeutic targets in HD patients. The HD CAG repeat...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2009
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2714728/ https://ncbi.nlm.nih.gov/pubmed/19465745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp242 |
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