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Factors associated with HD CAG repeat instability in Huntington disease

BACKGROUND: The Huntington disease (HD) CAG repeat exhibits dramatic instability when transmitted to subsequent generations. The instability of the HD disease allele in male intergenerational transmissions is reflected in the variability of the CAG repeat in DNA from the sperm of male carriers of th...

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Библиографические подробности
Главные авторы: Wheeler, V C, Persichetti, F, McNeil, S M, Mysore, J S, Mysore, S S, MacDonald, M E, Myers, R H, Gusella, J F, Wexler, N S
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Group 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705129/
https://ncbi.nlm.nih.gov/pubmed/17660463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmg.2007.050930
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