Bub1 regulates chromosome segregation in a kinetochore-independent manner

The kinetochore-bound protein kinase Bub1 performs two crucial functions during mitosis: it is essential for spindle checkpoint signaling and for correct chromosome alignment. Interestingly, Bub1 mutations are found in cancer tissues and cancer cell lines. Using an isogenic RNA interference compleme...

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Detaylı Bibliyografya
Asıl Yazarlar: Klebig, Christiane, Korinth, Dirk, Meraldi, Patrick
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2009
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711590/
https://ncbi.nlm.nih.gov/pubmed/19487456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200902128
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