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Centrosome age regulates kinetochore–microtubule stability and biases chromosome mis-segregation

The poles of the mitotic spindle contain one old and one young centrosome. In asymmetric stem cell divisions, the age of centrosomes affects their behaviour and their probability to remain in the stem cell. In contrast, in symmetric divisions, old and young centrosomes are thought to behave equally....

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Gasic, Ivana, Nerurkar, Purnima, Meraldi, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579388/
https://ncbi.nlm.nih.gov/pubmed/26287477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07909
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