Chromosome Segregation Is Biased by Kinetochore Size

Chromosome missegregation during mitosis or meiosis is a hallmark of cancer and the main cause of prenatal death in humans. The gain or loss of specific chromosomes is thought to be random, with cell viability being essentially determined by selection. Several established pathways including centroso...

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Veröffentlicht in:Curr Biol
Hauptverfasser: Drpic, Danica, Almeida, Ana C., Aguiar, Paulo, Renda, Fioranna, Damas, Joana, Lewin, Harris A., Larkin, Denis M., Khodjakov, Alexey, Maiato, Helder
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954971/
https://ncbi.nlm.nih.gov/pubmed/29706521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2018.03.023
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