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Bub1 regulates chromosome segregation in a kinetochore-independent manner
The kinetochore-bound protein kinase Bub1 performs two crucial functions during mitosis: it is essential for spindle checkpoint signaling and for correct chromosome alignment. Interestingly, Bub1 mutations are found in cancer tissues and cancer cell lines. Using an isogenic RNA interference compleme...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711590/ https://ncbi.nlm.nih.gov/pubmed/19487456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200902128 |
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