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Interrogating the Molecular Basis for Multiple Macrolactone Ring Formation by the Pikromycin Polyketide Synthase
The pikromycin polyketide synthase (PKS) is unique in its ability to generate both 12-and 14-membered ring macrolactones. As such, dissection of the molecular basis for controlling metabolic diversity in this system remains an important objective for understanding modular PKS function and expanding...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2707933/ https://ncbi.nlm.nih.gov/pubmed/17719493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2007.07.013 |
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